- Antipyrine is known from the poisonous effects it produced in old-school practice.
- Many fatal cases were recorded and there can be little doubt that its injudicious use determined a fatal issue in many cases that have remained unrecorded.
- Antipyrines action is very like that of Acetan, in producing collapse, but it has more effect on the skin, causing scarlpt rash and edemaSwelling caused by excess fluid in tissuesA condition characterized by an excess of watery fluid collecting in the cavities or tissues of the body..
- It is one of the drugs that induce leucocytosis, similar to ergotine, salicylates and tuberculin.
- Antipyrine acts especially on the vasomo tor centers, causing dilation of the capillaries of the skin and circumscribed patches of hyperemia a nd swelling.
- In large doses, it causes profuse perspiration, dizziness, cyanosisBluish discoloration of the skinA bluish or purplish discoloration of the skin and mucous membranes due to low oxygen levels in the blood., somnolence, albumen and blood in urine.
- Acute erythemaRedness of the skin from inflammationAn abnormal redness of the skin caused by congestion and dilation of the capillaries, often from inflammation. multiform.
- COMMENTS-A young female patient who took Antipyrine on her own account whenever she thought she might be going to have a headache, developed intense dysmenorrhea🩺 DysmenorrheaClinical Disease Treatment Profile: Read homeopathic remedies, dietary recommendations, and natural therapeutic options. (to which she was not subject) with depression.
- This was only removed after she had dis continued the drug.
- Later, she took Phenac etin with result that an eruption of erythema appeared on both cheeks, which peeled after a few days and recurred persistently.
- It would seem that the drug is ho meopathic to some forms of neuralgiaSharp nerve pain along a nerve pathIntense, shooting, or burning pain that radiates along the course of one or more nerves..
- One patient had Cheyne-Stokes respiration.
- Erythema appears first on face and arms, last on legs.
- Hansen mentioned its use in bedwetting and nosebleed.
- Better from hot drinks
